Serum concentrations of modafinil could possibly be reduced to your clinically significant extent inside the existence of medicine that induce CYP3A4. These include things like rifampin, phenytoin, St John Wort, and efavirenz.
Melding av bivirkninger Kontakt lege, apotek eller sykepleier dersom du opplever bivirkninger. Dette gjelder også bivirkninger som ikke er nevnt i pakningsvedlegget. Du kan også melde fra om bivirkninger direkte by way of meldeskjema som finnes på nettsiden til Direktoratet for medisinske produkter: /pasientmelding. Ved å melde fra om bivirkninger bidrar du med informasjon om sikkerheten ved bruk av dette legemidlet. Les avsnitt 5. Hvordan du oppbevarer Modiodal Oppbevares utilgjengelig for barn. Bruk ikke dette legemidlet etter utløpsdatoen som er angitt på gjennomtrykksfolien og kartongen etter «EXP».
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En gruppe lidelser og tilstander i hjernen som kan forårsake funksjonsforstyrrelser som karakteriseres av ulike former av anfall, enten med eller uten innvirkning på bevisstheten, og med eller uten krampeanfall.
As a way to get a prescription for modafinil, a individual must have a sound health care cause for utilizing the drug, for instance narcolepsy or obstructive rest apnea. On top of that, the prescription has to be penned by a licensed medical professional and loaded in a accredited pharmacy. The use of modafinil for non-healthcare reasons, for example with the aim to improve cognitive overall performance or to remain awake for very long amounts of time, is strictly prohibited and may lead to authorized repercussions.[184][185]
Modafinil is likewise available to astronauts aboard the International Space Station with the administration of fatigue because of circadian dyssynchrony in orbit.[79]
Modafinil is really a regulated drug that is definitely approved for use only as being a remedy for distinct Ailments, so there is no Formal suggestion for dosage when it can be made use of off-label for a nootropic. A lot of consumers report ideal final results with dosages in between fifty–200 mg daily.[36]
They observed that anterior cingulate activation elevated in the majority of subjects, and working memory improved in the minority of subjects, but no subjects with minimized anterior cingulated activation demonstrated enhanced Doing the job memory. A put up-hoc Examination of the info also showed that individuals that enhanced on modafinil had low baseline scores. These benefits indicated to your authors that lower dose modafinil might have an anterior cingulate cortex mediated impact on Doing the click here job memory in impaired schizophrenics with individual properties.
Narcolepsy: 1st-line remedy; Modafinil is used to deal with the daytime exhaustion linked to narcolepsy, and it has not been demonstrated to further improve signs or symptoms of cataplexy.
Trinnpris angis for ikke-patenterte legemidler, hvor det foreligger generisk konkurranse mellom legemidler som Direktoratet for medisinske produkter har vurdert som likeverdige.
Snooze Diseases may well cut down your power to respond rapidly. However modafinil assists hold you awake, you still may not be ready to safely and securely do things which require quick reactions (which include driving).
Stay away from other hazardous actions until finally you know how modafinil will impact your level of wakefulness.
It is far from known irrespective of whether modafinil passes into breast milk or if it could harm a nursing newborn. Tell your medical professional if you are breast-feeding a infant.
The novel wake-selling agent modafinil has actually been in use to the treatment method of many slumber Conditions for just a few years and is particularly now going through scientific trials for its use from the therapy of stimulant habit, but its Main mechanism of motion stays elusive. Preceding laboratory reports have revealed that modafinil has antioxidative and neuroprotective effects, which have not Earlier been recommended to become associated with its wake-selling results. On the other hand, the latest research indicates that cost-free radicals could be connected with rest induction and cellular damage, suggesting that a typical concentrate on of motion may perhaps mediate modafinil’s capacity to oppose both equally of these outcomes.